Membrane Channels & Receptors

Investigators at UVa are studying communication between cells, such as cardiac cells, through gap junction channels. Calcium channels are important in excitable cells including neurons and muscle cells. G protein coupled receptors are the most abundant drug targets, and UVa research seeks a better structural understanding of coupling G protein activation to ligand binding. Channels in the outer membranes of gram-negative bacteria are responsible for nutrient and antibiotic uptake and therefore important drug targets.                               

 

Faculty Members: Paula Barrett, Douglas Bayliss, Linda Columbus, Brant Isakson, Lukas Tamm, Mark Yeager

Research Faculty: Mark Daniels, Kelly Dryden, Binyong Liang, Michael Purdy